스킵네비게이션

생리학

연구실소개

생리학연구실은 양식생물, 나아가 수산생물의 체내에서 일어나는 물리·화학적 생명 현상을 다루는 연구실이다. 「생리」라 하는 것은 생물체의 번식, 호흡, 소화, 감각, 내·외분비와 순환 등에 관련된 체내의 모든 생명현상을 일컫는 말이다. 자연생태계에서 생물들은 종 고유의 생리적 특성을 유지하며 살아가고 있지만, 양식생물들은 인위적으로 조절된 환경에서 사육되기 때문에 본래의 생리적 특성이 무시되고 있다. 따라서 인위적 사육에 의해 발생하는 문제점들을 해결하는 데 있어 양식 대상종의 생리상태에 대한 이해는 물론, 생물적응의 한계를 파악한 후 양식생물의 종별 생리모델을 정립하는 것은 양식생물의 성장과 번식의 극대화로 이어진다. 본 연구실은 양식품종들의 최적 종보존을 비롯하여 성장과 면역에 관여하는 성장인자를 탐색하여 양식대상종들의 안정적인 산업을 조성하는 기반 기술을 개발하기 위해 연구와 실험에 매진하고 있다.

지도교수님

최윤희교수

주소부산광역시 남구 용소로 45 부경대학교

전화번호051-629-5915

홈페이지

국외학술지

  • Selvakumari ulagesan, Taek-Jeong Nam, Youn Hee Choi (2021). Biogenic preparation and characterization of Pyropia yezoensis silver nano particles (P.yAgNPs) and their antibacterial activity against Pseudomonas aeruginosa. Bioprocess and Biosystems Engineering 44, 443-452.
  • Selvakumari ulagesan, Jeong-Wook Choi, Taek-Jeong Nam, Youn Hee Choi (2021). Characterization of recombinant protein ferritin from Pyropia yezoensis (rPyFer) and its biological activities. Food Science and Biotechnology 29(11), 1501-1509.
  • Wonsuk Choi, Ali Hamidoghli, Jinho Bae, Seonghun Won, Youn Hee Choi, Kang-Woong Kim, Bong-Joo Lee, Sang-Woo Hur, Hyonsob Han, Sungchul C. Bai (2020). On-farm evaluation of dietary animal and plant proteins to replace fishmeal in sub-adult olive flounder Paralichthys olivaceus. Fisheries and Aquatic Sciences. 23-3.
  • Jeong Hwan Oh, Taek-Jeong Nam, Youn Hee Choi (2020). Activation of BDNF-mediated PKA signaling in the ventral hippocampus by Capsosiphon fulvescens glycoproteins alleviates. Journal of Functional Foods, 73, 104112.
  • Sung-Jun Back, Su-Jin Park, Ji-Sung Moon, Seung-Baek Lee, Su-Jung Jo, Taek-Jeong Nam, Sungchul C. Bai, In-Soo Kong, Kyeong-Jun Lee, Bong-Joo Lee, Sang-Woo Hur, Seunghyung Lee, Youn Hee Choi (2020). The effects of dietary heat-killed probiotics bacteria additives in low-fishmeal feed on growth performance, immune responses, and intestinal morphology in juvenile olive flounder Paralichthys olivaceus. Aquaculture Reports, 18, 100415.
  • Tankeng Terence Nguafack, Won Je Jang, Md Tawheed Hasan, Youn Hee Choi, Sungchul C. Bai, Eun-Woo Lee, Bong-Joo Lee, Sang Woo Hur, Seunghyung Lee, In-Soo Kong (2020). Effects of dietary non-viable Bacillus sp. SJ-10, Lactobacillus plantarum, and their combination on growth, humoral and cellular immunity, and streptococcosis resistance in olive flounder (Paralichthys olivaceus). Research in Veterinary Science, 131, 177-185.
  • Ping Liu, Jeong-Wook Choi, Min-Kyeong Lee, Youn-Hee Choi, Taek-Jeong Nam (2020). Spirulina protein promotes skin wound repair in a mouse model of full-thickness dermal excisional wound. International Journal of Molecular Medicine. 46(1) 351-359.
  • Selvakumari ulagesan, Jeong-Wook Choi, Taek-Jeong Nam, Youn Hee Choi (2020). Peptidyl-prolyl isomerase and Biological activities of Recombinant protein Cyclophilin from Pyropia yezoensis (PyCyp). Protein Expression and Purification, 172, 105636.
  • Jeong Hwan Oh, Taek-Jeong Nam, Youn Hee Choi (2020). Capsosiphon fulvescens glycoproteins enhance probiotics-induced cognitive improvement in aged rats. Nutrients, 12(3), 837.
  • Ji-Sung Moon, Youn Hee Choi (2020). Role of the insulin-like growth factor system in gonad sexual maturation in Pacific oyster Crassostrea gigas. Fisheries and Aquatic Sciences, 23-3.
  • Eun-Young Kim, Youn Hee Choi (2019). Regulation of addcutor muscle growth by the IGF-I-Akt/PKB pathway in triploid Pacific oyster, Crassostrea gigas. Fisheries and Aquatic Sciences, 22-19.
  • Jae-Hun Jung, Jeong-Wook Choi, Min-Kyeong Lee, Youn-Hee Choi, Taek-Jeong Nam (2019). Effect of Cyclophilin from Pyropia yezoensis on the proliferation of intestinal epithelial cells by EGFR/Ras signaling pathway. Marine Drugs, 17(5), 297.
  • Min-Kyeong Lee, Jeong-Wook Choi, Youn-Hee Choi, Taek-Jeong Nam (2019). Pyropia yezoensis peptide protects against dexamethasone-induced myotube atrophy in C2C12 myotubes. Marine Drugs, 17(5), 284.
  • Su-Jin Jeong, Jeong-Wook Choi, Min-Kyeong Lee, Youn-Hee Choi, Taek-Jeong Nam (2019). Spirulina protein promotes the migration and proliferation in IEC-6 cells by activating EGFR/MAPK siganling pathway. Marine Drugs, 17(4), 205.
  • Ping Liu, Jeong-Wook Choi, Min-Kyeong Lee, Youn-Hee Choi, Taek-Jeong Nam (2019). Wound healing potential of spirulina protein on CCD-986sk cells. Marine Drugs, 17(2), 130.
  • Joo Hyun Park, Jeong-Wook Choi, Min-Kyeong Lee, Youn Hee Choi, Taek Jeong Nam (2019). Protective effects of Hizikia fusiforme and Chlorella sp. extracts against lead acetate-induced hepatotoxicity in rats. Fisheries and Aquatic Sciences, 22:2.
  • Ji-Sung Moon, Youn Hee Choi (2019). Multiplex PCR for the rapid detection of insulin-like growth factor in the Pacific oyster, Crassostrea gigas: a useful indicator for growth assessment. Molecular Biology Reports, 46(1) 1023-1031.
  • PING LIU, MIN-KYEONG LEE, JEONG-WOOK CHOI, YOUN-HEE CHOI, TAEK-JEONG NAM (2019). Crude protein from spirulina increases the viability of CCD‑986sk cells via the EGFR/MAPK signaling pathway. International Journal of Molecular Medicine 43(2), 771-778.
  • Min-Kyeong Lee, Jeong-Wook Choi, Youn-Hee Choi, Taek-Jeong Nam (2018). Pyropia yezoensis Protein Prevents Dexamethasone-Induced Myotube Atrophy in C2C12 Myotubes. Marine Drugs, 16(12), 497.
  • Min-Kyeong Lee, Jeong-Wook Choi, Youn-Hee Choi, Taek-Jeong Nam (2018). Pyropia yezoensis Protein Supplementation Prevents Dexamethasone-Induced Muscle Atrophy in C57BL/6 Mice. Marine Drugs, 16(9), 328.
  • Youn Hee Choi, Eun-Yong Kim, Taek Jeong Nam (2018). Involvement of insulin-like growth factor on intraspecific variation in growth of Pacific oyster Crassostrea gigas during winter. Fisheries Science, 84(6), 1017-1024.
  • Eun-Young Kim, Youn Hee Choi, Teak-Jeong Nam (2018). Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. International Journal of Molecular Medicine, 42(2), 789-798.
  • Kang-Woong Kim, Taek Jeong Nam, Youn Hee Choi (2018). Protein variation and involvement of insulin-like growth factor during embryonic development in the olive flounder Paralichthys olivaceus. Fisheries and Aquatic Sciences, 21:4.
  • Youn Hee Choi, Kang-Woong Kim, Dong-Soo Kim, Taek Jeong Nam (2017). Evaluation of different Pyropia yezoensis extracts as feed additives for growth and immunity of Japanese flounder Paralichthys olivaceus. Fisheries Science, 83(5), 819-826.
  • Kang-Woong Kim, Kyoung-Duck Kim, Hyon-Sob Han, Seonghun Won, Mohammad Moniruzzaman, Jin-Hyeok Lee, Youn Hee Choi, Sungchul C. Bai (2017). Evaluation of the Dietary Protein Requirement of a Selectively Bred (F-5 Generation) Strain of Olive Flounder, Paralichthys Olivaceus. Turkish Journal of Fisheries and Aquatic Sciences, 17(5):1009-1016.
  • EUN-YOUNG KIM, YOUN HEE CHOI, CHANG GEUN CHOI, TAEK- JEONG NAM (2017). Effects of the cyclophilin-type peptidylprolyl cis-trans isomerase from Pyropia yezoensis against hydrogen peroxide-induced oxidative stress in HepG2 cells. MOLECULAR MEDICINE REPORTS, 15 (6), 4132-4138.
  • MIN-KYEONG LEE, YOUNG-MIN KIM, IN-HYE KIM, YOUN-HEE CHOI, TAEK-JEONG NAM (2017). Pyropia yezoensis peptide PYP1-5 protects against dexamethasone-induced muscle atrophy through the downregulation of atrogin1/MAFbx and MuRF1 in mouse C2C12 myotubes. MOLECULAR MEDICINE REPORTS, 15(6), 3507-3514.
  • JEONG HWAN OH, EUN-YOUNG KIM, YOUN HEE CHOI, TAEK- JEONG NAM (2017). Negative regulation of ERK1/2 by PI3K is required for the protective effects of Pyropia yezoensis peptide against perfluorooctane sulfonate-induced endoplasmic reticulum stress. MOLECULAR MEDICINE REPORTS, 15(5), 2583-2587.
  • Cho-Rong Kim, Young-Min Kim, Min-Kyeong Lee, In-Hye Kim, Youn-Hee Choi, Taek-Jeong Nam (2017). Pyropia yezoensis peptide promotes collagen synthesis by activating the TGF-β/Smad signaling pathway in the human dermal fibroblast cell line Hs27. International Journal of Molecular Medicine, 39(1), 31-38.
  • Jeong-Wook Choi, In-Hye Kim, Young-Min Kim, Min-Kyeong Lee, Youn Hee Choi, Taek Jeong Nam (2016). Protective effect of Pyropia yezoensis glycoprotein on chronic ethanol consumption-induced hepatotoxicity in rats. MOLECULAR MEDICINE REPORTS, 14(5), 4881-4886.
  • Youn Hee Choi, Eun-Young Kim, Koji Mikami, Taek Jeong Nam (2015). Chemoprotective effects of a recombinant protein from Pyropia yezoensis and synthetic peptide against acetaminophen-induced Chang liver cell death. International Journal of Molecular Medicine, 36(2), 369-376.
  • Eun-Young Kim, Youn Hee Choi, Jung Im Lee, In-Hye Kim, Taek-Jeong Nam (2015). Antioxidant activity of oxygen evolving enhancer protein 1 purified from Capsosiphon fulvescens. Journal of Food Science, 80(6), H1412-H1417.
  • Youn Hee Choi, Taek Jeong Nam (2015). Toxicity of cryoprotective agents and signaling of insulin-like growth factor in hen clam (Mactra chinensis) embryos. CryoLetters, 36(3), 158-164.
  • MIN-KYEONG LEE, IN-HYE KIM, YOUN-HEE CHOI, JEONG-WOOK CHOI, YOUNG-MIN KIM, TAEK-JEONG NAM (2015). The proliferative effects of Pyropia yezoensis peptide on IEC-6 cells are mediated through the epidermal growth factor receptor signaling pathway. International Journal of Molecular Medicine, 35(4), 909-914.
  • YOUN HEE CHOI, KENICHI YAMAGUCHI, TATSUYA ODA, TAEK JEONG NAM (2015). Chemical and mass spectrometry characterization of the red alga Pyropia yezoensis chemoprotective protein (PYP) : Protective activity of the N-terminal fragment of PYP1 against acetaminophen-induced cell death in Chang liver cells. International Journal of Molecular Medicine, 35(1), 271-276.
  • Youn Hee Choi, Taek Jeong Nam (2014). Influences of the toxicity of cryoprotective agents on the involvement of insulin-like growth factor-I receptor in surf clam (Spisula sachalinensis) larvae. CryoLetters, 35(6), 537-543.
  • Youn Hee Choi, Young Jin Chang (2014). Influence developmental stage, protective additive and concentration of CPA on cryopreservation of Pacific oyster (Crassostrea gigas) larvae. CryoLetters, 35(6), 495-500.
  • Jung Im Lee, In-Hye Kim, Youn Hee Choi, Eun-Young Kim, Taek-Jeong Nam (2014). PTP1B inhibitory effect of alkyl p-coumarates from Calystegia soldanella. Natural Product Communications 9(11), 1585-1588.
  • Youn Hee Choi, Bong-Joo Lee, Taek Jeong Nam (2015). Effect of dietary inclusion of Pyropia yezoensis extract on biochemical and immune responses of olive flounder Paralichthys olivaceus. Aquaculture, 435(1), 347-353.
  • MIN-KYEONG LEE, IN-HYE KIM, YOUN-HEE CHOI, TAEK-JEONG NAM (2015). A peptide from Porphyra yezoensis stimulates the proliferation of IEC-6 cells by activating the insulin-like growth factor I receptor signaling pathway. International Journal of Molecular Medicine, 35(2), 533-538.
  • SU-JIN PARK, JINA RYU, IN-HYE KIM, YOUN-HEE CHOI, TAEK-JEONG NAM (2015). Activation of the mTOR signaling pathway in breast cancer MCF-7 cells by a peptide derived from Porphyra yezoensis. Oncology Reports, 33(1), 19-24.
  • SU-JIN PARK, JINA RYU, IN-HYE KIM, YOUN-HEE CHOI, TAEK-JEONG NAM (2014). Induction of apoptosis by a peptide from Porphyra yezoensis: Regulation of the insulin-like growth factor I receptor signaling pathway in MCF-7 cells. International Journal of Oncology, 45(3), 1011-1016.
  • JINA RYU, SU-JIN PARK, IN-HYE KIM, YOUN HEE CHOI, TAEK-JEONG NAM (2014). Protective effect of porphyra-334 on UVA-induced photoaging in human skin fibroblasts. International Journal of Molecular Medicine, 34(3), 796-803.
  • Eun-Young Min, In-Hye Kim, Jungim Lee, Eun-young Kim, Youn-Hee Choi, Taek Jeong Nam (2014). The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines. International Journal of Oncology, 45(1), 47-56.
  • Youn Hee Choi, Kang-Woong Kim, Hyon-Sob Han, Taek Jeong Nam, Bong-Joo Lee (2014). Dietary Hizikia fusiformis glycoprotein-induced IGF-I and IGFBP-3 assosiciated to somatic growth, polyunsaturated fatty acid metabolism, and immunity in juvenile olive flounder Paralichthys olivaceus. Comparative Biochemistry and Physiology, Part A : Molecular & Integrative Physiology, 167(1), 1-6.
  • Youn Hee Choi, Taek Jeong Nam, Kuwano K (2013). Cryopreservation of gametophytic thalli of Porphyra yezoensis (Rhodophyceae) by one-step fast cooling. Journal of Applied Phycology, 25(2), 531-535.
  • Youn Hee Choi, Jeong Yong Lee, Young Jin Chang (2008). The influence of developmental stages and protective additives on cryopreservation of surf clam (Spisula sachalinensis) larvae. Journal of Envrionmental Biology, 29(4), 461-463.
  • Kang-Woong Kim, Yong-Jin Kang, Se-Min Choi, Xiaojie Wang, Youn-Hee Choi, Sungchul C. Bai, Jae-Yoon Jo, Jeong-Yeol Lee (2005). Optimum dietary protein levels and protein to energy ratios in olive flounder Paralichthys olivaceus. Journal of the world aquaculture society, 36(2), 165-178.
  • Youn Hee Choi, Young Jin Chang (2003). The influence of cooling rate, developmental stage and the addition of sugar on the cryopreservation of larvae of the pearl oyster (Pinctada fucata martensii). Cryobiology, 46(2), 190-193.
  • Youn Hee Choi, Young Jin Chang (2003). Gametogenic Cycle of the Transplanted-Cultured Pearl Oyster, Pinctada fucata martensii (Bivalvia: Pteriidae) in Korea. Aquaculture, 220, 781-790.
  • Kang-Woong Kim, Xiaojie Wang, So-Min Choi, Sungehul C. Bai, Youn-Hee Choi, Seong-Hee Choi (2002). Long-term evaluation of extruded diets compared with raw fish moist diet for growing Korean rockfish, Sebastes schlegeli (Hilgendorf). Aquaculture Research, 33(12), 979-985.
생리학연구실인원

재학생

이름, 과정, 이메일로 구성된 연구실인원표입니다.
재학생 이름 과정
박사과정 박수진 박사수료 후 연구생
박사과정 이현규 박사 3년
박사과정 신민규 박사 3년
박사과정 이용환 박사 2년
석사과정 문성환 석사수료
석사과정 이승백 석사 2년
석사과정 조수정 석사 2년
석사과정 Tran Thanh Biet 석사 2년
석사과정 옥장민 석사 1년
석사과정 조인규 석사 1년
석사과정 이승롱 석사 1년
석사과정 서봉승 석사 1년
학부과정 이예인 학부 4년
학부과정 이은서 학부 4년
학부과정 황소연 학부 4년
학부과정 화지현 학부 3년

졸업생

구분,성명,학위논문명,일자로 구성된표입니다.
구분 성명 학위논문명 일자
학사 서진송 2018.02
이승욱 2020.02
석사 ADJELAKARA MOSSUS JEAN-BLAISE (Cameroon),
KOICA-PKNU International Graduate Program
2020.02
문지성 Expression of IGF System in Various Tissues and Seasonal Growth of
the Diploid and Triploid Pacific oyster, Crassostrea gigas
2020.02
김한식 Evaluation of sperm quality in Anguilla japonica
using computer-assisted sperm analysis (CASA) system
2020.08
Ayobi Zabiullah (Afghanistan), KOICA-PKNU International Graduate Program 2021.02
백성준 The effects of low-fishmeal diet to sexual maturationin
the sub-adult female olive flounder (Paralichthys olivaceus)
2021.02
제형우 Effects of dietary gamma aminobutyric acid as a feed additive in
juvenile olive flounder, Paralichthys olivaceus
2021.02
(공동지도)
박사 최원석 Evaluation of four commercial feed additives and three isolated
probiotics to replace antibiotics in juvenile olive flounder
Paralichthys olivaceus fed the low fishmeal diet
2021.02
(공동지도)
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부산 남구 용소로 45 부경대학교 대연캠퍼스 수산과학대학 해양바이오신소재학과TEL. 051-629-5909~10FAX. 051-629-5908